Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50077569'
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077569(Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]ind...)
Affinity DataKi:  1.90nMAssay Description:In vitro high binding affinity towards Dopamine receptor D2 by the displacement of [3H]quinpirole radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077569(Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]ind...)
Affinity DataKi:  1.90nMAssay Description:Affinity of compound for Dopamine receptor D2 in rat striatal membrane determined for antagonist state (low affinity state, D2 Low) with [3H]spiperon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077569(Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]ind...)
Affinity DataKi:  36nMAssay Description:In vitro low binding affinity towards Dopamine receptor D2 by the displacement of [3H]spiperone radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077569(Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]ind...)
Affinity DataKi:  36nMAssay Description:Affinity of compound for Dopamine receptor D2 in rat striatal membrane determined for antagonist state (low affinity state, D2 Low) with [3H]spiperon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Wyeth-Ayerst Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50077569(Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]ind...)
Affinity DataKi:  107nMAssay Description:Affinity for the Dopamine receptor D2S was determined using membranes from CHO cells labeled with [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed