Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'DCN1-like protein 1' and Ligand = 'BDBM50271350'
TargetDCN1-like protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50271350(CHEMBL4128331 | US12012467, Compound DI-67)
Affinity DataKd:  37nMAssay Description:Binding affinity to biotin labeled recombinant N-terminal His6-tagged human DCN1 (58 to 259 residues) expressed in Escherichia coli Rosetta2 cells by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50271350(CHEMBL4128331 | US12012467, Compound DI-67)
Affinity DataIC50: 413nMAssay Description:Displacement of (S)-N1-((19S,22S)-26-Amino-19-carbamoyl-1-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1,13,21-trioxo-5,8,11-tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50271350(CHEMBL4128331 | US12012467, Compound DI-67)
Affinity DataIC50: 413nMAssay Description:The Fluorescence Polarization (FP) competitive binding assays were performed to accurately determine the binding affinities of our DCN1 inhibitors. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetDCN1-like protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50271350(CHEMBL4128331 | US12012467, Compound DI-67)
Affinity DataKi:  54nMAssay Description:Displacement of (S)-N1-((19S,22S)-26-Amino-19-carbamoyl-1-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)-1,13,21-trioxo-5,8,11-tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2020
Entry Details Article
PubMed