Report error Found 7 Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit B' and Ligand = 'BDBM50423645'
TargetDNA gyrase subunit B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assayMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMT: 25°CAssay Description:Inhibition of Mycobacterium smegmatis DNA GyrB domain assessed as inhibition of inorganic phosphate release after 100 mins at room temperature by ATP...More data for this Ligand-Target Pair
Affinity DataIC50: 154nMAssay Description:Inhibition of Escherichia coli JM109 DNA gyrase subunit B assessed as ATP hydrolysis by ATPase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Mycobacterium smegmatis GyrB ATPase activity expressed in Escherichia coli BL21 (DE3) after 2 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Escherichia coli JM109 DNA gyrase subunit B assessed as DNA triple helix formation by supercoiling assayMore data for this Ligand-Target Pair
Affinity DataKd: 28nMAssay Description:Binding affinity to Escherichia coli GyrBMore data for this Ligand-Target Pair