Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM31788'
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM31788(thieno[2,3-d]pyrimidine deriv., 2k)
Affinity DataIC50: 300nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

LigandPNGBDBM31788(thieno[2,3-d]pyrimidine deriv., 2k)
Affinity DataIC50: 3.00E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2009
Entry Details Article
PubMed