Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50038270'
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  2.20E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  600nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  2.50E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  2.20E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed