Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50038272'
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038272(2-Amino-5-methyl-8-(3-methyl-butyl)-2,8-dihydro-3H...)
Affinity DataKd:  3.30E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038272(2-Amino-5-methyl-8-(3-methyl-butyl)-2,8-dihydro-3H...)
Affinity DataKd:  4.50E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038272(2-Amino-5-methyl-8-(3-methyl-butyl)-2,8-dihydro-3H...)
Affinity DataKd:  700nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038272(2-Amino-5-methyl-8-(3-methyl-butyl)-2,8-dihydro-3H...)
Affinity DataKd:  1.80E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed