Compile Data Set for Download or QSAR
Report error Found 1 Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM535'
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 535BDBM535((3S,5R)-5-methyl-1,1-dioxo--thiolan-3-yl N-[(2S,3R...)
Affinity DataIC50: 82nMpH: 5.5 T: 2°CAssay Description:The IC50 values for the compounds were determined using purified HIV-1 Protease. Inhibition of the cleavage of the peptide H-Val-Ser-Gln-Asn-(L-beta-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2004
Entry Details Article
PubMed