Found 2 Enz. Inhib. hit(s) with Target = 'Dimer of Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM580' TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of Florida College Of Medicine
University Of Florida College Of Medicine
Affinity DataKi: 0.0210nM ΔG°: -63.4kJ/molepH: 4.7 T: 2°CAssay Description:The inhibition constants Ki were determined by monitoring the inhibition of hydrolysis of the chromogenic substrate using a Hewlett-Packard 8452A spe...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.330nM ΔG°: -56.3kJ/molepH: 6.0 T: 2°CAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Substrates and cleavage fragments...More data for this Ligand-Target Pair
