Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase CLK1/CLK4' and Ligand = 'BDBM50239782'
TargetDual specificity protein kinase CLK1/CLK4(Human)
German University In Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239782BDBM50239782(CHEMBL4082113)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CLK1/4 in human T24 cells assessed as down regulation of EGFR expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1/CLK4(Human)
German University In Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239782BDBM50239782(CHEMBL4082113)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of CLK1/4 in human MDA-MB-231 cells assessed as down regulation of EGFR expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1/CLK4(Human)
German University In Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239782BDBM50239782(CHEMBL4082113)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of CLK1/4 in human T24 cells assessed as down regulation of HDAC1 expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1/CLK4(Human)
German University In Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239782BDBM50239782(CHEMBL4082113)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CLK1/4 in human MDA-MB-231 cells assessed as down regulation of S6 kinase expression after 3 days by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2019
Entry Details Article
PubMed