Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase CLK1' and Ligand = 'BDBM50623175'
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623175BDBM50623175(CHEMBL5424844)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CLK1 using GRSRSRSRSRSRSRS as substrate incubated for 15 mins in presence of ATP by gamma32P-ATP based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623175BDBM50623175(CHEMBL5424844)
Affinity DataKi:  51nMAssay Description:Binding affinity to NanoLuc-fused CLK1 (unknown origin) transfected in HEK293T cells assessed as target engagement by measuring inhibition constant i...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623175BDBM50623175(CHEMBL5424844)
Affinity DataEC50:  250nMAssay Description:Binding affinity to NanoLuc-fused CLK1 (unknown origin) transfected in HEK293T cells assessed as target engagement incubated for 3 hrs by tracer K5 b...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
German University In Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623175BDBM50623175(CHEMBL5424844)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of NanoLuc-fused CLK1 (unknown origin) transfected in HEK293T cells incubated for 3 hrs in presence of ATP by tracer K5 based NanoBRET ass...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed