Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Enoyl-[acyl-carrier-protein] reductase [NADH] FabI' and Ligand = 'BDBM8732'
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
Affinium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8732((2E)-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]-3...)
Affinity DataIC50: 139nMAssay Description:Inhibition of Escherichia coli FabI assessed as effect on NAD(P)H consumptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Escherichia coli (strain K12))
Affinium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8732((2E)-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]-3...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Escherichia coli FabIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Glaxosmithkline

LigandPNGBDBM8732((2E)-N-methyl-N-[(1-methyl-1H-indol-2-yl)methyl]-3...)
Affinity DataIC50: 560nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2006
Entry Details Article
PubMed