Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50494963'
TargetEstrogen receptor(Human)
Marquette University

US Patent
LigandPNGBDBM50494963(CHEMBL3099431 | US10570077, Compound 13)
Affinity DataKd:  160nMAssay Description:Twelve compounds from Schemes 1 and 2 were screened using fluorescence polarization, for their ability to bind ERα (Table 1). Only six compounds...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
Go to US Patent

TargetEstrogen receptor(Human)
Marquette University

US Patent
LigandPNGBDBM50494963(CHEMBL3099431 | US10570077, Compound 13)
Affinity DataKd:  160nMAssay Description:Displacement of FITC-estradiol from human ERalpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Marquette University

US Patent
LigandPNGBDBM50494963(CHEMBL3099431 | US10570077, Compound 13)
Affinity DataIC50: 484nMAssay Description:Agonist activity at ERalpha (unknown origin) after 22 hrs by cell-based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed