Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50526382'
TargetFatty acid synthase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50526382(CHEMBL4466578)
Affinity DataIC50: 33nMAssay Description:Inhibition of full length recombinant human FASN using acetyl-CoA/malonyl-CoA as substrate preincubated for 60 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50526382(CHEMBL4466578)
Affinity DataIC50: 70nMAssay Description:Inhibition of FASN in human BT474 cells preincubated for 1 hr followed by [14C]-acetate addition and measured after 4 hrs by scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed