Found 83 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM18627' 
Affinity DataKi: 0.0900nMAssay Description:Displacement of fluormone GS Red from human glucocorticoid receptor after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.100nMAssay Description:Inhibition of human glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]DEX from human glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.299nMAssay Description:Displacement of [3H]-dexamethasone from human glucocorticoid receptor expressed in HEK293 cells by scintillation counting based radioligand competiti...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in recombinant baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Inhibition of glucocorticoid receptor dependent alkaline phosphatase activityMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Binding affinity was determined for human glucocorticoid receptor(hGR).More data for this Ligand-Target Pair
Affinity DataKi: 0.820nMAssay Description:Binding affinity to glucocorticoid receptor in SW1353 cells by whole-cell binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in human A549 cells assessed as inhibition of corticoid-induced transcription by glucocortic...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of radiolabeled Dexamethasone from human GRMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expressionMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Antagonist activity at human glucocorticoid receptor in SW1353 cells assessed as inhibition of dexamethasone-induced luciferase expression by MMTV5 r...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Antagonist activity at glucocorticoid receptor in human HepG2 cells assessed as inhibition of dexamethasone-induced tyrosine amino transferase activi...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human GR expressed in hGRAF cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]-dexamethasone from cytosolic fraction of human recombinant glucocorticoid receptor by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of glucocorticoid receptor mediated tyrosine amino transferase activityMore data for this Ligand-Target Pair
Affinity DataKi: 169nMAssay Description:Inhibition of human GR transcriptional activation by HepTAT cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.00800nMAssay Description:Inhibition of CHO-K1 cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.298nMAssay Description:Antagonist activity against glucocorticoid receptor (unknown origin) expressed in HEK293 cells by GRE-dependent luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at cloned glucocorticoid receptor-ligand binding domain expressed in african green monkey COS7 cells by GAL4 luciferase reporter ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at glucocorticoid receptor by Gal4-DNA binding domain-hormone receptor LBD one-hybrid assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at human GR ligand binding domain expressed in african green monkey COS7 cells in presence of Dexamethasone by Gal4 hybrid assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at glucocorticoid receptor ligand binding domain by two hybrid assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.640nMAssay Description:Antagonist activity at glucocorticoid receptor in human HeLa cells assessed as reduction in dexamethasone-induced luciferase activity by dual-Glo luc...More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human GR assessed as reduction in dexamethasone-induced transactivationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of antagonist activity towards glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against human glucocorticoid receptor (hGR)More data for this Ligand-Target Pair
Affinity DataIC50: 0.950nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in african green monkey CV1 cells co-transfected with MMTV-Luc by luciferase reporter ...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]dexamethasone from human Glucocorticoid receptor (GR)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Dexamethasone binding to Glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nM EC50: 4.80nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the 3(H)-dexamethasone from the receptor an IC50 value (the concentration required to inhibit 50% of the binding of 3(...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMpH: 8.0 T: 2°CAssay Description:For compounds able to displace the radiolabeled ligand (competitor) from the receptor an IC50 value (the concentration required to inhibit 50% of the...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced GRE-linked luciferase reporter gene ac...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells assessed as inhibition of corticoid-induced transcription after 16 hrs by glucocor...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity against glucocorticoid receptor in rat H4-IIE cells assessed as inhibition of dexamethasone-induced receptor transactivation pre-...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:In vitro antagonist potency in transactivation assay in NIH3T3 cells expressing glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Displacement of fluormone tracer from full length human recombinant glucocorticoid receptor expressed in baculovirus expression system incubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at glucocorticoid receptor ligand binding domain expressed in african green monkey COS7 cells co-transfected with Gal4-LBD by luc...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at human GR expressed in CHO-K1 cells assessed as reduction in dexamethasone-induced response incubated for 20 hrs by luciferase ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in CHO-K1 cells harboring firefly luciferase gene after 20 hrs by One-Glo luciferase r...More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in CHO-K1 cells assessed as inhibition of glucocorticoid receptor-dexamethasone coacti...More data for this Ligand-Target Pair
Affinity DataIC50: 4.68nMAssay Description:Antagonist activity at glucocorticoid receptor in human A549 cells transfected with MMTV luciferase reporter gene assessed as inhibition of dexametha...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Activity at GR assessed as ability to antagonize dexamethasone-induced MMTV luciferase reporter gene transactivation in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
