Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50214946'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50214946((Z)-5-(2-methyl-3-(trifluoromethyl)benzylidene)-10...)
Affinity DataKi:  2.60nMAssay Description:Displacement of radiolabeled dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50214946((Z)-5-(2-methyl-3-(trifluoromethyl)benzylidene)-10...)
Affinity DataIC50:  2.60nMAssay Description:Antagonist activity at GR assessed as inhibition of dexamethasone-induced GRE activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50214946((Z)-5-(2-methyl-3-(trifluoromethyl)benzylidene)-10...)
Affinity DataIC50:  15nMAssay Description:Activity at GR assessed as repression of TNFalpha and IL 1beta induced E-selectin responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed