Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Growth hormone secretagogue receptor type 1' and Ligand = 'BDBM21941'
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM21941(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  1.90nMAssay Description:Agonist activity at human GHS receptor expressed in H4 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM21941(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  1.90nMpH: 7.2 T: 2°CAssay Description:The functional FLIPR assay was developed from H4 glioma cells in which expression of the endogenous human GHS receptor was enhanced by RAGE-activatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2008
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM21941(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  1.92nMAssay Description:Inhibition of human growth hormone secretagogue receptor assessed as measuring intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM21941(2-{5-[(1S)-1-(2-amino-2-methylpropanamido)-2-(benz...)
Affinity DataEC50:  1.92nMAssay Description:Agonist activity at GHS receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed