Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Growth hormone secretagogue receptor type 1' and Ligand = 'BDBM50544353'
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544353(CHEMBL4649860)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544353(CHEMBL4649860)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544353(CHEMBL4649860)
Affinity DataIC50: 40nMAssay Description:Displacement of [His[125I]]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50544353(CHEMBL4649860)
Affinity DataIC50: 42nMAssay Description:Displacement of [His[125I]]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed