Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EZH2' and Ligand = 'BDBM435609'
TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

US Patent
LigandPNGBDBM435609(US10570121, Example 119 | US10570121, Example 118)
Affinity DataKi:  0.100nMAssay Description:A. Compound preparation1. Prepare 10 mM stock solutions in 100% DMSO from solid material2. Serial dilute 10 mM compound stocks either 2 or 3-fold in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Pfizer

US Patent
LigandPNGBDBM435609(US10570121, Example 119 | US10570121, Example 118)
Affinity DataKi:  15nMAssay Description:A. Compound preparation1. Prepare 10 mM stock solutions in 100% DMSO from solid material2. Serial dilute 10 mM compound stocks either 2 or 3-fold in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent