Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Integrin alpha-4/beta-1' and Ligand = 'BDBM50505781'
TargetIntegrin alpha-4/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505781(CHEMBL4461668)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of fibronectin binding to alpha4bbeta1 isolated from human Jurkat E6.1 cells incubated for 1 hr by scintillation-proximity assay based com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505781(CHEMBL4461668)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as inhibition of VCAM1-induced cell adhesion pre-incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505781(CHEMBL4461668)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as reduction in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed