Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Integrin alpha-V/beta-3' and Ligand = 'BDBM50505779'
TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505779(CHEMBL4461771)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of fibronectin binding to human recombinant alphaVbeta3 expressed in HEK293 cells incubated for 1 hr by scintillation-proximity assay base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505779(CHEMBL4461771)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50505779(CHEMBL4461771)
Affinity DataIC50: 41nMAssay Description:Antagonist activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as reduction in fibronectin-induced cell adhesion pre-incubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed