Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with Target = 'Lanosterol synthase' and Ligand = 'BDBM50095601'
TargetLanosterol synthase(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50095601([4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)-phenyl]-(4-ch...)
Affinity DataIC50: 22nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in Trypanosoma bruceiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50095601([4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)-phenyl]-(4-ch...)
Affinity DataIC50: 35nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095601([4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)-phenyl]-(4-ch...)
Affinity DataIC50: 58nMAssay Description:In vitro percent inhibitory activity of the compound against rat microsomal OSC enzyme at 1 uM concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095601([4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)-phenyl]-(4-ch...)
Affinity DataIC50: 58nMAssay Description:Concentration for the inhibition of rat microsomal oxidosqualene cyclase-lanosterol synthase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50095601([4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)-phenyl]-(4-ch...)
Affinity DataIC50: 92nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in Pneumocystis cariniiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095601([4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)-phenyl]-(4-ch...)
Affinity DataIC50: 160nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50095601([4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)-phenyl]-(4-ch...)
Affinity DataIC50: 400nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed