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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Lanosterol synthase' and Ligand = 'BDBM50133285'
TargetLanosterol synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50133285((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...)
Affinity DataIC50:  4.30nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in T. bruceiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50133285((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...)
Affinity DataIC50:  4.60nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in P. cariniiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Rattus norvegicus)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50133285((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...)
Affinity DataIC50:  49nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
University of Utah

Curated by ChEMBL
LigandPNGBDBM50133285((E)-3-Carboxy-acrylateallyl-{6-[4-(4-chloro-benzoy...)
Affinity DataIC50:  71nMAssay Description:Tested for Oxidosqualene-lanosterol cyclase inhibition in T. cruziMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed