Report error Found 10 Enz. Inhib. hit(s) with Target = 'Leucine-rich repeat serine/threonine-protein kinase 2' and Ligand = 'BDBM4814'
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human N-terminal GST-tagged LRRK2 after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of GST-tagged LRRK2 G2019S mutant (1326 to 2527 residues) (unknown origin) using peptide as substrate incubated for 15 mins in presence of...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human GST-tagged human LRRK2 (1326 to 2527 residues)More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of human LRRK2 (1885 to 2132) using 5-Fluo-Ahx-RLGRDKYKTLRQIRQGNTK-OH as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of GST-tagged LRRK2 G2019S/A2016T mutant (1326 to 2527 residues) (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of GST-tagged LRRK2 G2019S mutant (1326 to 2527 residues) (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataKd: 76nMAssay Description:Binding constant for LRRK2 kinase domainMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of GST-tagged LRRK2 (1326 to 2527 residues) (unknown origin) using peptide as substrate incubated for 15 mins in presence of ATP by immuno...More data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant human GST-tagged human LRRK2 G2019S mutantMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
The University of Sydney
Curated by ChEMBL
The University of Sydney
Curated by ChEMBL
Affinity DataKd: 110nMAssay Description:Binding constant for LRRK2 kinase domainMore data for this Ligand-Target Pair
