Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM36512'
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandChemical structure of BindingDB Monomer ID 36512BDBM36512(CID164227 | Cylcophellitol, 3 | US11826435, Compou...)
Affinity DataKi:  152nM ΔG°:  -40.5kJ/mole IC50: 150nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Leiden University

LigandChemical structure of BindingDB Monomer ID 36512BDBM36512(CID164227 | Cylcophellitol, 3 | US11826435, Compou...)
Affinity DataKi:  152nMAssay Description:Inactivation solutions contained a final concentration of 16.55 nM of Cerezyme (Recombinant GCase) in 200 μL of Reaction Buffer (50 mM acetate, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2024
Entry Details
US Patent