Report error Found 16 Enz. Inhib. hit(s) with Target = 'Lysosomal acid glucosylceramidase' and Ligand = 'BDBM50182801'
Affinity DataKi: 1.70nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Affinity DataKi: 1.70nMpH: 7.0Assay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMpH: 7.0Assay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human GCase assessed as reduction of 4-methylumbelliferone liberation using 4-methylumbelliferyl-beta-glucopyranoside as substrate prei...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of GCase assessed as 4-methylumbelliferone release assay after 30 mins by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human lysosomal beta-glucosidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of human lysosome beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant GCase (unknown origin) using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at pH 4.5More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
Affinity DataEC50: 300nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate assess...More data for this Ligand-Target Pair
Affinity DataEC50: 390nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cell assessed as GCase level incubated for 5 days by immunocytochemistry a...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of GCase in patient derived fibroblast cells using 5'pentafluorobenzoylaminofluorescein-di-beta-D-glucoside as substrate assessed as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of bovine liver beta-glucosidase assessed as production of 4-methylumbelliferone using 4-methylumbelliferyl beta-D-glucoside as substrate ...More data for this Ligand-Target Pair
