Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'MAP kinase-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM168241'
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 168241BDBM168241(US9669031, 69 8-fluoro-3,3-dimethyl-6-(pyrimidin-4...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of full length N-terminal GST-tagged recombinant human MNK2 expressed in baculovirus expression system using Ac-TATKSGSTTKNR-NH2 as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2020
Entry Details Article
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Effector Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 168241BDBM168241(US9669031, 69 8-fluoro-3,3-dimethyl-6-(pyrimidin-4...)
Affinity DataIC50: 10nMT: 2°CAssay Description:Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
US Patent