Report error Found 17 Enz. Inhib. hit(s) with Target = 'Macrophage colony-stimulating factor 1 receptor' and Ligand = 'BDBM4814'
Affinity DataKd: 2nMAssay Description:Binding constant for CSF1R kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:Binding affinity to CSF1RMore data for this Ligand-Target Pair
Affinity DataKd: 2nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
Affinity DataKd: 2.5nMAssay Description:Binding constant for CSF1R kinase domainMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibition of CSF1R in mouse BMDM cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant His-tagged human CSF1R catalytic domain expressed in baculovirus expression system using TAMRA-KKKSPGEYVNIEFG as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of CSF1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of CSF1R (unknown origin) incubated for 30 mins in presence of ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Inhibition of human FMS expressed in growth factor dependent mouse FDC-P1 cells assessed as inhibition of FMS-mediated cell proliferation in presence...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R in bortezomib Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous o...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R in human bortezomib-resistant ANBL6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R in human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prol...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R in human U-266 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolifer...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R in Melphalan Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous on...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CSF1R in human ANBL-6 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolife...More data for this Ligand-Target Pair
