Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50052256'
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052256(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataIC50: 2.50E+4nMAssay Description:The compound was tested for inhibitory effect on second messenger formation in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052256(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052256(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at mGluR1alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Parc Club Orsay Université

Curated by ChEMBL
LigandPNGBDBM50052256(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against Metabotropic glutamate receptor 1 in the rat LLC-PK1/HEK 293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052256(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of mGluR1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052256(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataKi:  2.50E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052256(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against mGluR1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50052256(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataEC50: >3.00E+5nMAssay Description:The compound was tested for effect on second messenger formation in BHK cells expressing mGluR1aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed