Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Metallo-beta-lactamase type 2' and Ligand = 'BDBM361114'
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361114((R)-4-(4-(N-(pyrrolidin-3-yl)sulfamoyl)-3-sulfamoy...)
Affinity DataIC50: 0.0200nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361114((R)-4-(4-(N-(pyrrolidin-3-yl)sulfamoyl)-3-sulfamoy...)
Affinity DataIC50: 0.0200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361114((R)-4-(4-(N-(pyrrolidin-3-yl)sulfamoyl)-3-sulfamoy...)
Affinity DataIC50: 0.271nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2019
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM361114((R)-4-(4-(N-(pyrrolidin-3-yl)sulfamoyl)-3-sulfamoy...)
Affinity DataIC50: 0.271nMAssay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
US Patent