Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM50456347'
TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50456347(CHEMBL4207117 | US11001575, Example 80)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of full length human N-terminal MAHHHHHH-tagged ERK2 expressed in Escherichia coli BL21 (DE3) using ATF2-GFP as substrate after 30 mins by...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50456347(CHEMBL4207117 | US11001575, Example 80)
Affinity DataIC50: 4.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 1(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50456347(CHEMBL4207117 | US11001575, Example 80)
Affinity DataIC50: 4.30nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
In DepthDetails
US Patent