Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM39341'
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]methylscopolamine binding to muscarinic M3 receptor in submaxillary salivary glands of rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataIC50: 600nMAssay Description:Binding affinity for glandular muscarinic acetylcholine receptor M3 in rat assayed using 0.3 nM [3H]N-methylscopolamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataIC50: 956nMAssay Description:Displacement of [3H]-NMS binding to human Muscarinic acetylcholine receptor M3 using membranes from transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  28nMAssay Description:Ability to displace [3H]N-methylscopolamine (NMS) from M3 receptor in rat submaxillary gland homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  47.9nMAssay Description:Displacement of [3H]N-methylscopolamine chloride from human cloned muscarinic M3 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  81.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  138nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  158nMAssay Description:Binding affinity to human M3 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  158nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  174nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  174nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic receptor (M3) in rat submaxillary gland homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2018
Entry Details

TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  174nMAssay Description:Compound was tested for inhibiting [3H]N-Methyl-scopolamine Binding to Muscarinic receptor (M3) in Rat Submaxillary GlandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

TargetMuscarinic acetylcholine receptor M3(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  240nMAssay Description:Inhibition of binding of [3H]N-methylscopolamine to muscarinic acetylcholine receptor M3 of transfected rat A9L cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  320nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  450nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Dipartimento Di Scienze Farmaceutiche - Università

Curated by ChEMBL
LigandPNGBDBM39341(PIRENZEPINE DIHYDROCHLORIDE | SMR000058502 | MLS00...)
Affinity DataKi:  720nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details
PubMed