Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'NACHT, LRR and PYD domains-containing protein 3' and Ligand = 'BDBM50647995'
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50647995(CHEMBL5597392)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin stimulated human PBMC assessed as reduction in IL-1beta release pretreated with LPS for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50647995(CHEMBL5597392)
Affinity DataIC50: 15nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin stimulated mouse BMDMs assessed as reduction in IL-1beta release pretreated with LPS for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50647995(CHEMBL5597392)
Affinity DataKd:  18nMAssay Description:Binding affinity to human NLRP3 by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed