Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Neuraminidase' and Ligand = 'BDBM5024'
TargetNeuraminidase(Influenza A virus (strain A/Brevig Mission/1/1918 ...)
University of Victoria

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5024BDBM5024((-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylb...)
Affinity DataKi:  0.830nMAssay Description:Inhibition of Influenza A virus (A/Brevig Mission/1/1918(H1N1)) recombinant soluble neuraminidase using 2'-4(methylumbelliferyl)-alpha-D-N-acetylneur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (A/Singapore/1/57(H2N2)))
Biocryst Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 5024BDBM5024((-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylb...)
Affinity DataIC50: 1nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2005
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5024BDBM5024((-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylb...)
Affinity DataIC50: 1.40nMAssay Description:inhibitory concentration required to inhibit neuraminidase enzyme from different strains of influenza A virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Brevig Mission/1/1918 ...)
University of Victoria

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5024BDBM5024((-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylb...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of Influenza A virus (A/Brevig Mission/1/1918(H1N1)) recombinant soluble neuraminidase using 2'-4(methylumbelliferyl)-alpha-D-N-acetylneur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetNeuraminidase(Influenza B virus (B/Lee/40))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5024BDBM5024((-)-(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylb...)
Affinity DataIC50: 11nMAssay Description:inhibitory concentration required to inhibit neuraminidase enzyme from different strains of influenza B virus.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed