Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50021657'
LigandPNGBDBM50021657(CHEMBL3297839)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of JAK2/TYK2 in human whole blood assessed as inhibition of IL-23-induced STAT-3 phosphorylation preincubated for 45 mins followed by IL-2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50021657(CHEMBL3297839)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of JAK2/TYK2 in human whole blood assessed as inhibition of IL-12-induced STAT-4 phosphorylation preincubated for 45 mins followed by IL-1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed