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Found 4 Enz. Inhib. hit(s) with Target = 'Pantetheinase' and Ligand = 'BDBM395107'
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395107(3-({2-[(pyridin-3- ylmethyl)amino] pyrimidin-5- yl...)
Affinity DataIC50:  4nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395107(3-({2-[(pyridin-3- ylmethyl)amino] pyrimidin-5- yl...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395107(3-({2-[(pyridin-3- ylmethyl)amino] pyrimidin-5- yl...)
Affinity DataIC50:  4.60nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395107(3-({2-[(pyridin-3- ylmethyl)amino] pyrimidin-5- yl...)
Affinity DataIC50:  11.2nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent