Report error Found 55 Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor alpha' and Ligand = 'BDBM28681'
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARalpha ligand binding domain expressed in human HeLa cells co-transfected with Gal4-DBD assessed as transcriptional activation...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPAR alpha in a HepG2 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPAR alpha in HepG2 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10E+3nMAssay Description:Agonist activity at human PPARalpha by transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human liver PPAR alpha expressed in HEK293 cells by PPAR-GAL4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.46E+3nMAssay Description:Agonist activity at human PPARalpha in CV1 cells by GAL4 transactivation assay after 24 hrsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha by transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Agonist activity at human PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
Affinity DataEC50: 3.46E+3nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey CV-1 by co-transfected with GAL4 by by dual-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 39nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human HepG2 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha receptor by cell based transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro agonist activity tested for transactivation in human PPAR alpha-Gal4 chimeric COS-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha by luciferase reporter transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation of Gal4-fused human PPARalpha DNA binding domain expressed in african green monkey CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in COS-1 cells co-transfected with Gal4 after 24 hrs by luciferase reporter gene ...More data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at PPARalpha in HEK293 cells by GAL4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human PPARalpha by transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant PPARalpha LBD expressed in african green monkey COS7 cells coexpressing GAL4 by luciferase reporter gene transa...More data for this Ligand-Target Pair
Affinity DataEC50: 3.46E+3nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in african green monkey CV1 cells co-transfected with fused Gal4-DBD by transacti...More data for this Ligand-Target Pair
Affinity DataEC50: 1.06E+4nMAssay Description:Agonist activity at human GAL4-tagged PPARalpha chimeric receptor expressed in HEK cells by transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Displacement of radiolabeled GW-2331 from human PPAR alpha by SPA binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10E+3nMAssay Description:In vitro transactivation of human Peroxisome proliferator activated receptor alpha (hPPARalpha)More data for this Ligand-Target Pair
Affinity DataEC50: 4.10E+3nMAssay Description:In vitro activation of human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10E+3nMAssay Description:In vitro transactivation using receptor transactivation assay against hPPAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:In vitro transcription activation on human peroxisome proliferator activated receptor-alpha (PPAR alpha)More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Effective concentration for human peroxisome proliferator-activated receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10E+3nMAssay Description:Effective concentration for human peroxisome proliferator-activated receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alpha in Gal4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:In vitro transactivation of human Peroxisome proliferator activated receptor alpha measured in PPAR-GAL4 chimeric COS-1 cellMore data for this Ligand-Target Pair
Affinity DataEC50: >3.20E+4nMAssay Description:Effective concentration against human Peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:In vitro effective concentration against human peroxisome proliferator activated receptor alpha/Gal4 in transactivation assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.20E+4nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro binding affinity for human PPAR alpha in SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of tritium labeled ligand from human PPARalpha by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards human peroxidase proliferator activated receptor alpha (hPPARalpha)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Receptor binding affinity to human Peroxisome proliferator activated receptor alpha against [3H]-NNC 0061-4655 radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from hPPARalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from G...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Mean inhibitory concentration against human peroxisome proliferator activated receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]L-783483 from human PPAR alpha by SPA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of [3H2]nTZD3 from GST-tagged human recombinant PPARalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:In vitro binding affinity for human peroxisome proliferator activated receptor alpha using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of PPARalphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H2]nTZD3 from human recombinant GST-fused PPARalpha expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
