Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform' and Ligand = 'BDBM50469457'
LigandChemical structure of BindingDB Monomer ID 50469457BDBM50469457(CHEMBL4286698)
Affinity DataKd:  1.00E+3nMAssay Description:Inhibition of human PI3Kalpha (108 to 1068 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50469457BDBM50469457(CHEMBL4286698)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human wild-type partial length PI3Kalpha (R108 to N1068 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50469457BDBM50469457(CHEMBL4286698)
Affinity DataKi:  4.20E+3nMAssay Description:Binding affinity to recombinant N-terminal His6-tagged P110alpha catalytic domain (unknown origin) after 1 hr by TR-FRET displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed