Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform' and Ligand = 'BDBM36409'
LigandChemical structure of BindingDB Monomer ID 36409BDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  42nMAssay Description:Binding constant for PIK3CG kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 36409BDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataKd:  42nMAssay Description:Inhibition of human PI3Kgamma (144 to 1102 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 36409BDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 500nMAssay Description:Class I PI3-Ks can be either purchased (p110α/p85α, p110β/p85α, p110 /p85α from Upstate, and p110γ from Sigma) or ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 36409BDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 500nMAssay Description:This assay is relatively simple, reasonably sensitive, and the peptide substrate can be adjusted both in terms of sequence and concentration to meet ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 36409BDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PI3K p110-gamma (unknown origin) in presence of [gamma-32P]ATP by radioactivity based kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed