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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Plasma kallikrein' and Ligand = 'BDBM528099'
TargetPlasma kallikrein(Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM528099(1-({4-[(5-fluoro-2-oxopyridin-1-yl)methyl]phenyl}m...)
Affinity DataIC50: 6.70nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
Go to US Patent

TargetPlasma kallikrein(Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM528099(1-({4-[(5-fluoro-2-oxopyridin-1-yl)methyl]phenyl}m...)
Affinity DataIC50: 6.70nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2023
Entry Details
Go to US Patent

TargetPlasma kallikrein(Human)
Kalvista Pharmaceuticals

US Patent
LigandPNGBDBM528099(1-({4-[(5-fluoro-2-oxopyridin-1-yl)methyl]phenyl}m...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed