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Report error Found 9 Enz. Inhib. hit(s) with Target = 'Platelet-derived growth factor receptor alpha/beta' and Ligand = 'BDBM50239948'
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataEC50:  1.57E+3nMAssay Description:Inhibition of PD-1/PD-L1 interaction in human Jurkat T cells cocultured with artificial antigen presenting cells assessed as increase in TCR-mediated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataEC50:  1.58E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human PD-1/PD-L1 interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of C-terminal 3S-IG-tagged recombinant human PD-1 (25 to 167 residues)/C-terminal 6xHis-tagged recombinant human PD-L1 (18 to 239 residues...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PD-1 (unknown origin)/PD-L1 (unknown origin) interaction by HTRF binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PD-1 (unknown origin)/PD-L1 (unknown origin) interaction by HTRF binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataIC50: 3nMAssay Description:Inhibition of C-terminal his tagged human PD-1/human Fc tagged PDL-1 interaction expressed in HEK293 cells incubated for 2 hrs AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as induction of PD-L1 dimerization incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataIC50: 12nMAssay Description:Inhibition of PD-1/PD-L1 interaction (unknown origin) incubated for 60 min by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed