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Report error Found 10 Enz. Inhib. hit(s) with Target = 'Programmed cell death 1 ligand 1' and Ligand = 'BDBM50239947'
TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:Binding affinity to PDL1 (unknown origin) assessed as reduction in PDL1/PD1 protein-protein interaction preincubated for 15 mins followed by PD1 addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human PD-L1 (18 to 134 residues) expressed in Escherichia coli BL21 (DE3) incubated for 1 hr by spectrophometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:Inhibition of His-tagged human PD-L1 preincubated for 60 mins followed by substrate addition measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:Inhibition of PD-L1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataIC50: 18nMAssay Description:Binding affinity to His-tagged PD-L1 (unknown origin) assessed as reduction in PD-L1/PD1-Ig interaction preincubated with PD-L1 for 15 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2019
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataKd:  37nMAssay Description:Binding affinity towards His-tagged recombinant human PD-L1 measured by MST dimerization binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataKd:  135nMAssay Description:Binding affinity to human PDL1 assessed as dissociation constant by MST methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataKd:  169nMAssay Description:Binding affinity to recombinant human PD-L1 expressed in HEK293 cells by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50239947(US9872852, Example 202 | CHEMBL4089730 | US2023030...)
Affinity DataKd:  1.37E+3nMAssay Description:Binding affinity to his-tagged mouse PD-L1 expressed in HEK293 cells assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed