Report error Found 6 Enz. Inhib. hit(s) with Target = 'Protein O-GlcNAcase' and Ligand = 'BDBM205424'
Affinity DataEC50: 53nMT: 2°CAssay Description:The ELISA portion of the assay was performed in a black Maxisorp 96-well plate that was coated overnight at 4° C. with 100 uL/well of the cell ly...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 53nMAssay Description:Inhibition of OGA in rat PC12 cells assessed as OGlcNAcylated protein level incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human O-GlcNAcaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nM ΔG°: -47.1kJ/molepH: 7.0 T: 2°CAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Enzymatic reactions were carried out in a reaction containing 50 mM NaH2PO4, 100 mM NaCl and 0.1% BSA (pH 7.0) using 2 mM 4-Methylumbelliferyl N-acet...More data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Inhibition of recombinant human OGAMore data for this Ligand-Target Pair
