Report error Found 19 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM420297'
Affinity DataIC50: 23nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant SARS-COV2 main protease using Mca-AVLQ-SGFR-Lys-NH2 as substrate by FRET based cleavage assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal recombinant SARS CoV 2 3CL protease expressed in Escherichia coli BL21-DE3 cells using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant SARS-CoV-2 Main protease expressed in Escherichia coli using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate preincubated for 10...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of SARS-CoV2 main proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Recombinant SARS-CoV-2 Mpro was expressed and purified from Escherichia coli (E. coli) (18, 25). A fluorescently labeled substrate, MCA-AVLQ SGFR-Lys...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of SARS-CoV-2 3CL proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant SARS-CoV-2 Main protease expressed in Escherichia coli using MCA-AVLQSGFR-Lys(DNP)-Lys-NH2 as fluorogenic substrate preincu...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of SARS-CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate by FRET analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of 2019-nCoV-2 3CLp using fluorescent substrate by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of SARS CoV-2 main protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as substrate preincubated for 10 mins followed by substrate addition and m...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of full length GST-tagged SARS-CoV-2 Main protease expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataEC50: 330nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataEC50: 720nMAssay Description:Inhibition of Severe acute respiratory syndrome coronavirus 2 MPro incubated for 24 hrs by plaque assayMore data for this Ligand-Target Pair
Affinity DataEC50: 720nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Affinity DataIC50: 858nMAssay Description:Inhibition of SARS-CoV-2 3CL protease expressed in Escherichia coli BL21 (DE3) cells assessed as change in relative fluorescence unit using MCA-TSAVL...More data for this Ligand-Target Pair
