Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM50405454'
TargetReplicase polyprotein 1ab(2019-nCoV)
Kansas State University Research Foundation

US Patent
LigandPNGBDBM50405454(CHEMBL4850298 | US12180156, Parental aldehyde)
Affinity DataEC50:  500nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2025
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Kansas State University Research Foundation

US Patent
LigandPNGBDBM50405454(CHEMBL4850298 | US12180156, Parental aldehyde)
Affinity DataIC50: 380nMAssay Description:Inhibition of N-terminal His6-tagged full length SARS-CoV-2 3CLpro using FAM-SAVLQ as substrate preincubated with enzyme for 1 hr followed by susbtra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kansas State University Research Foundation

US Patent
LigandPNGBDBM50405454(CHEMBL4850298 | US12180156, Parental aldehyde)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant SARS-CoV-2 Main protease expressed in Escherichia coli BL21 (DE3) using Abz-SVTLQSG-Y(NO2)-R as substrate incubated for 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kansas State University Research Foundation

US Patent
LigandPNGBDBM50405454(CHEMBL4850298 | US12180156, Parental aldehyde)
Affinity DataIC50: 400nMAssay Description:Inhibition of SARS-CoV-2 3CL protease measured after 10 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kansas State University Research Foundation

US Patent
LigandPNGBDBM50405454(CHEMBL4850298 | US12180156, Parental aldehyde)
Affinity DataIC50: 400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed