Found 21 Enz. Inhib. hit(s) with Target = 'Retinoic acid receptor alpha' and Ligand = 'BDBM31892' 
Affinity DataKi: 22nMAssay Description:Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 7nMAssay Description:Binding affinity against retinoic Acid alpha receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Mus musculus)
University of Alabama at Birmingham
Curated by ChEMBL
University of Alabama at Birmingham
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of [3H]-ATRA binding to mouse Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Relative activity against Retinoic acid receptor RAR alpha compared to ATRAMore data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 304nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Mus musculus)
University of Alabama at Birmingham
Curated by ChEMBL
University of Alabama at Birmingham
Curated by ChEMBL
Affinity DataKd: 7nMAssay Description:Dissociation constant for binding to Retinoic acid receptor alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at human RAR-alpha expressed in CHO-K1 cells by PathHunter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 102nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Transcriptional activation in CV-1 cells expressing retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 90nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed retinoic acid receptor RAR-alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Agonist activity for retinoic acid receptor RAR alpha in transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 102nMAssay Description:Transcriptional activation for RAR alpha receptorMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Compound was tested for binding affinity against retinoic acid receptor using 5 nM of [3H]-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Compound was tested for functional activity in CV-1 cells transfected with an expression vector for retinoic acid receptor alpha using transactivatio...More data for this Ligand-Target Pair
Affinity DataKd: 93nMAssay Description:Inhibition of [3H]-ATRA binding to human Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 102nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Binding affinity against retinoic Acid alpha receptors cotransfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Transcriptional activation in CV-1 cells expresing human Retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
Affinity DataKd: 93nMAssay Description:Inhibition of [3H]-RA binding to retinoic acid receptor RAR alphaMore data for this Ligand-Target Pair
