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Report error Found 5 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM50365218'
TargetRho-associated protein kinase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of N-terminal His-tagged human ROCK1 (3 to 543 residues) expressed in baculovirus infected Sf9 cells using biotin-Ahx-AKRRRLSSLRA-CONH2 as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of human recombinant N-terminal his-tagged ROCK1 (3-543) expressed in baculovirus infected Sf9 cells using Biotin-Ahx-AKRRLSSLRA-CONH2 sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)
Affinity DataIC50:  14nMAssay Description:Inhibition of ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)
Affinity DataIC50:  39nMAssay Description:Inhibition of N terminal histidine tagged human recombinant ROCK1 (3 to 543 residues) expressed in baculovirus infected Sf9 cells using biotin-Ahx-AK...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRho-associated protein kinase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50365218(CHEMBL1956071 | GSK screening, 29)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of N terminal histidine tagged human recombinant ROCK1 (3 to 543 residues) in HASMC cells incubated for 2 hrs by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails PubMed