Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'SYK Kinase' and Ligand = 'BDBM225519'
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225519(GTC000227A)
Show SMILES NCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C21H22N8O2S/c22-8-2-10-29(18-4-1-3-17-16(18)13-24-28-17)20-7-9-23-21(27-20)26-15-6-5-14-12-25-32(30,31)19(14)11-15/h1,3-7,9,11,13,25H,2,8,10,12,22H2,(H,24,28)(H,23,26,27)
Affinity DataIC50: 0.75nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225519(GTC000227A)
Show SMILES NCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C21H22N8O2S/c22-8-2-10-29(18-4-1-3-17-16(18)13-24-28-17)20-7-9-23-21(27-20)26-15-6-5-14-12-25-32(30,31)19(14)11-15/h1,3-7,9,11,13,25H,2,8,10,12,22H2,(H,24,28)(H,23,26,27)
Affinity DataIC50: 0.857nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225519(GTC000227A)
Show SMILES NCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C21H22N8O2S/c22-8-2-10-29(18-4-1-3-17-16(18)13-24-28-17)20-7-9-23-21(27-20)26-15-6-5-14-12-25-32(30,31)19(14)11-15/h1,3-7,9,11,13,25H,2,8,10,12,22H2,(H,24,28)(H,23,26,27)
Affinity DataIC50: 3.63nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed