Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'SYK Kinase' and Ligand = 'BDBM225523'
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225523(GTC000229A)
Show SMILES OC(=O)CCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C23H23N7O4S/c31-22(32)6-1-2-11-30(19-5-3-4-18-17(19)14-25-29-18)21-9-10-24-23(28-21)27-16-8-7-15-13-26-35(33,34)20(15)12-16/h3-5,7-10,12,14,26H,1-2,6,11,13H2,(H,25,29)(H,31,32)(H,24,27,28)
Affinity DataIC50: 1.19nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225523(GTC000229A)
Show SMILES OC(=O)CCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C23H23N7O4S/c31-22(32)6-1-2-11-30(19-5-3-4-18-17(19)14-25-29-18)21-9-10-24-23(28-21)27-16-8-7-15-13-26-35(33,34)20(15)12-16/h3-5,7-10,12,14,26H,1-2,6,11,13H2,(H,25,29)(H,31,32)(H,24,27,28)
Affinity DataIC50: 1.41nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225523(GTC000229A)
Show SMILES OC(=O)CCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C23H23N7O4S/c31-22(32)6-1-2-11-30(19-5-3-4-18-17(19)14-25-29-18)21-9-10-24-23(28-21)27-16-8-7-15-13-26-35(33,34)20(15)12-16/h3-5,7-10,12,14,26H,1-2,6,11,13H2,(H,25,29)(H,31,32)(H,24,27,28)
Affinity DataIC50: 2.47nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed