Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'SYK Kinase' and Ligand = 'BDBM225528'
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225528(GTC000234A)
Show SMILES Cc1nn(CCCO)c2cc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)ccc12
Show InChI InChI=1S/C25H27FN8O2/c1-16-18-8-7-17(13-23(18)34(32-16)10-4-12-36)29-25-27-15-20(26)24(30-25)33(9-3-11-35)22-6-2-5-21-19(22)14-28-31-21/h2,5-8,13-15,35-36H,3-4,9-12H2,1H3,(H,28,31)(H,27,29,30)
Affinity DataIC50: 1.87nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225528(GTC000234A)
Show SMILES Cc1nn(CCCO)c2cc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)ccc12
Show InChI InChI=1S/C25H27FN8O2/c1-16-18-8-7-17(13-23(18)34(32-16)10-4-12-36)29-25-27-15-20(26)24(30-25)33(9-3-11-35)22-6-2-5-21-19(22)14-28-31-21/h2,5-8,13-15,35-36H,3-4,9-12H2,1H3,(H,28,31)(H,27,29,30)
Affinity DataIC50: 2.46nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225528(GTC000234A)
Show SMILES Cc1nn(CCCO)c2cc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)ccc12
Show InChI InChI=1S/C25H27FN8O2/c1-16-18-8-7-17(13-23(18)34(32-16)10-4-12-36)29-25-27-15-20(26)24(30-25)33(9-3-11-35)22-6-2-5-21-19(22)14-28-31-21/h2,5-8,13-15,35-36H,3-4,9-12H2,1H3,(H,28,31)(H,27,29,30)
Affinity DataIC50: 4.79nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed