Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'SYK Kinase' and Ligand = 'BDBM225530'
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225530(GTC000236A)
Show SMILES COCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C22H23N7O3S/c1-32-11-3-10-29(19-5-2-4-18-17(19)14-24-28-18)21-8-9-23-22(27-21)26-16-7-6-15-13-25-33(30,31)20(15)12-16/h2,4-9,12,14,25H,3,10-11,13H2,1H3,(H,24,28)(H,23,26,27)
Affinity DataIC50: 1.48nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225530(GTC000236A)
Show SMILES COCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C22H23N7O3S/c1-32-11-3-10-29(19-5-2-4-18-17(19)14-24-28-18)21-8-9-23-22(27-21)26-16-7-6-15-13-25-33(30,31)20(15)12-16/h2,4-9,12,14,25H,3,10-11,13H2,1H3,(H,24,28)(H,23,26,27)
Affinity DataIC50: 2.69nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225530(GTC000236A)
Show SMILES COCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C22H23N7O3S/c1-32-11-3-10-29(19-5-2-4-18-17(19)14-24-28-18)21-8-9-23-22(27-21)26-16-7-6-15-13-25-33(30,31)20(15)12-16/h2,4-9,12,14,25H,3,10-11,13H2,1H3,(H,24,28)(H,23,26,27)
Affinity DataIC50: 4.34nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSYK Kinase(Homo sapiens (Human))
D3R

LigandPNGBDBM225530(GTC000236A)
Show SMILES COCCCN(c1ccnc(Nc2ccc3CNS(=O)(=O)c3c2)n1)c1cccc2[nH]ncc12
Show InChI InChI=1S/C22H23N7O3S/c1-32-11-3-10-29(19-5-2-4-18-17(19)14-24-28-18)21-8-9-23-22(27-21)26-16-7-6-15-13-25-33(30,31)20(15)12-16/h2,4-9,12,14,25H,3,10-11,13H2,1H3,(H,24,28)(H,23,26,27)
Affinity DataIC50: 4.88nMAssay Description:SYK assay_HTRFMore data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In DepthDetails PubMed